Deoxynivalenol

Molecular Formula：C15H20O6

Molecular weight：296.3

Cas number：51481-10-8

Merck index：13,10092

Source：Isolated from Fusarium sp.

Purity (TLC)：>99%

Purity(HPLC)：>99%

Appearance：White crystalline solid.

Melting point：151-153°C

Solubility：Clear colorless solution at 10mg/ml methanol /ETOAC

Long term storage：-20°C or less.Protect from light.

Hazard：Toxic mycotoxin.May be carcinogenic, mutagenic properties.

Product Description：

Naturally occuring mycotoxin produced by many species of Fusarium sp. deoxynivalenol may have effects on the immune system, There are no indications of carcinogenic, mutagenic or teratogenic effects.

Warning：

This product is not intended or approved for human, diagnostics or veterinary use. use of this product for human or animal testing is extremely hazardous and may result in disease, severe injury, or death.

Material safety data：

This material should be considered hazardous until information to the contrary becomes available. Do not ingest, swallow, or inhale. Do not get in eyes, on skin, or on clothing. Wash thoroughly after handling. This information contains some, but not all, of the information required for the safe and proper use of this material. Before use, the user must review the complete Material Safety Data Sheet.

This product meets the requirement of the specification.

Source： Isolated from Fusarium sp.

Synonyms：

Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane],trichothec-9-en-8-one deriv.; 4-Deoxynivalenol; 4-Desoxynivalenol;
DON;Dehydronivalenol;
Deoxynivalenol; NSC 269144;

Description：
Deoxynivalenol (DON，Vomitoxin) is a type B trichothecene. Itoccurs in grains such as wheat, barley, oats, rye, and maize, rice,sorghum. Deoxynivalenol (DON ) is produced by numerous strainof Fusarium and some other fungi. Deoxynivalenol
(DON ) poisonings occur both in humans and farm animals.
Deoxynivalenol (DON ) is highly toxic, producing a wide range ofimmunological disturbances and is particularly noted for inducingfeed refusal and emesis in pigs, hence the alternative name vomitoxiDeoxynivalenol (DON ) usually co-occures with other Fusariumtoxins, such as Zearalenone,Nivalenol and its derivates,as well asthe group of fumonisins.

cAs number： 51481-10-8
Merck index： 13,10092
Molecular weight： 296.3

Molecular Formula： C15H20O6

Solubilityinformation： Deoxynivalenol (DON ) is soluble in common polar organic solvents as acetonitrile, methanol and ethyl acetate, slightly soluble in water.

Appearance： White crystalline solid.

Melting point： 151-153℃

Solubility： Clear colorless solution at 10mg/ml methanol/ETOAC
Storage： -20℃ or less.Protect from light.
Acetonitrile solution of DON has been reported stable for 24 month atroom temperature. (Widestrand J.; Pettersson H.,Food Addit
Contam.2001 Nov;18(11)：987-92),

Applications：

The main toxic effect of Deoxynivalenol (DON ) is inhibition of protein synthesis via binding to the ribosome.

Warnings：

Toxic mycotoxin.LD50 = 46 mg/kg (oral, mice). DON has not been reported as having carcinogenic, teratogenic or mutagenic properties.

注：以上信息僅供參考，以產品附帶證書為準。